Cardiovascular Protection After Preeclampsia With Enalapril
NCT07222852 · Status: NOT_YET_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-10-30
Summary
The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
Conditions
- Preeclampsia
- Hypertensive Disorder of Pregnancy
- Hypertension
- Gestational Hypertension
- Gestational Hypertension After Childbirth
Interventions
- DRUG
-
Enalapril
First-line anti-hypertensive treatment with enalapril
- OTHER
-
Standard treatment
First-line anti-hypertensive treatment per standard of care
Sponsors & Collaborators
-
Women and Infants Hospital of Rhode Island
lead OTHER
Principal Investigators
-
Alisse Hauspurg, MD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-11-15
- Primary Completion
- 2027-10-15
- Completion
- 2027-10-15
- FDA Drug
- Yes
More Related Trials
-
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
NCT06220721 ·Status: RECRUITING ·Phase: NA
-
Lisinopril for Renal Protection in Postpartum Preeclamptic Women
NCT05016440 ·Status: WITHDRAWN ·Phase: NA
-
Blood Pressure After PREeclampsia/HELLP by SELF Monitoring Study
NCT03228082 ·Status: COMPLETED ·Phase: NA
-
Postpartum Evaluation of Nifedipine and Enalapril for Hypertension
NCT07023003 ·Status: RECRUITING ·Phase: PHASE4
-
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
NCT03298802 ·Status: RECRUITING ·Phase: PHASE3
-
Aggressive Versus Expectant Management of Severe Preeclampsia Remote From Term
NCT01164852 ·Status: COMPLETED ·Phase: NA
-
Aspirin for the Prevention of Preeclampsia in Women With Stage 1 Hypertension
NCT04908982 ·Status: UNKNOWN ·Phase: PHASE4
-
The PreEclampsia Postpartum Prevention Trial
NCT07199283 ·Status: RECRUITING ·Phase: NA
-
Cardiovascular Changes in Infants of Preeclampsia Mother
NCT04699825 ·Status: UNKNOWN ·Phase: NA
-
Chronic Remote Ischemic Preconditioning as a Complement to Conventional Prenatal Care for Preeclampsia
NCT05564988 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Early Vascular Adjustments to Prevent Preeclampsia
NCT04216706 ·Status: COMPLETED
-
A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)
NCT06785116 ·Status: RECRUITING ·Phase: PHASE4
-
Cardiac Dysfunction and Remodeling in Patients With Preeclampsia
NCT04162236 ·Status: UNKNOWN
-
Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia
NCT05937841 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Maternal Serum Markers Predicting Preeclampsia At Early Gestations
NCT05131282 ·Status: COMPLETED
-
Daily Aspirin Treatment After Preeclampsia
NCT06168461 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Preeclampsia: A Marker for Future Cardiovascular Risk in Women
NCT01519297 ·Status: SUSPENDED ·Phase: NA
-
First-trimester Prediction of Preeclampsia
NCT02189148 ·Status: COMPLETED
-
Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy
NCT05826925 ·Status: RECRUITING ·Phase: NA
-
Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia
NCT02307201 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Regulation of Placental Vascular Reactivity in Pregnancy-induced Hypertension
NCT00005208 ·Status: COMPLETED
-
Angiogenic Factors in the Conservative Management of Gestational Hypertension
NCT06123377 ·Status: RECRUITING ·Phase: NA
-
Renin and Prorenin in Pregnancy
NCT00005207 ·Status: COMPLETED
-
Vascular Biomarkers Predictive of the Progression From Hypertensive Disorders in Pregnancy to Preeclampsia in Pregnant Women
NCT04520048 ·Status: RECRUITING ·Phase: NA
-
Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure
NCT05679206 ·Status: RECRUITING