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Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

NCT06220721 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 618

Last updated 2025-05-11

No results posted yet for this study

Summary

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Conditions

  • Hypertension, Pregnancy-Induced

Interventions

DRUG

Nifedipine ER

Initiation of nifedipine ER postpartum at randomly assigned threshold during the first 6 weeks postpartum.

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • Medical College of Wisconsin

    lead OTHER

Principal Investigators

  • Anna Palatnik, MD · Medical College of Wisconsin

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-23
Primary Completion
2029-03-31
Completion
2029-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06220721 on ClinicalTrials.gov