The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey
NCT07173322 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2025-09-15
Summary
As there is limited knowledge regarding the impact of CAR-T Cell therapy on fertility, LLS has designed a Patient Survey to learn more about the impact on fertility in patients who have received/are receiving CAR-T Cell treatment. The insights gained from this survey will inform future treatment protocols and fertility preservation strategies.
Conditions
Sponsors & Collaborators
-
University of Florida
collaborator OTHER -
Lymphoma and Leukemia Society
lead OTHER
Principal Investigators
-
Nina Logan, MD · The Leukemia and Lymphoma Society
-
John J Ligon, MD · Univ of Florida, Gainesville
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-09
- Primary Completion
- 2026-02-09
- Completion
- 2026-02-09
Countries
- United States
Study Locations
More Related Trials
-
Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History
NCT06821685 ·Status: RECRUITING ·Phase: PHASE1
-
Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
NCT06253520 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Restoration of Immunity to Vaccine Preventable Diseases After CART-T Cell Therapy
NCT06333275 ·Status: RECRUITING
-
Autologous Antigen-activated Dendritic Cells in the Treatment of Patients With Breast Cancer
NCT03113019 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Intervention of CAR-T Against Cervical Cancer
NCT03356795 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies
NCT04266093 ·Status: ENROLLING_BY_INVITATION
-
Collection and Generation of Antigen-specific T-lymphocyte Cell Lines From Primary, Third-party, Related, and Unrelated Donors
NCT03114566 ·Status: TERMINATED
-
Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
NCT04815356 ·Status: RECRUITING ·Phase: PHASE1
-
Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy
NCT04745559 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure
NCT07230574 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands
NCT02203825 ·Status: COMPLETED ·Phase: PHASE1
-
A Therapeutic Protocol in Previous Failed ART Patients With High Total NK Cells
NCT03792997 ·Status: COMPLETED ·Phase: PHASE2
-
Clonal Fetal Mesenchymal Stem Cells (cfMSCs) for the Control of Immune-related Disorders
NCT03123458 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1
-
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
NCT05620342 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers
NCT05035407 ·Status: TERMINATED ·Phase: PHASE1
-
Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients
NCT04948619 ·Status: RECRUITING ·Phase: PHASE2
-
CD30 CAR for CD30+ NSGCT
NCT05634785 ·Status: COMPLETED ·Phase: PHASE2
-
Immune Profiling for Cancer Immunotherapy Response
NCT06116032 ·Status: RECRUITING
-
Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT03735589 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma
NCT00430053 ·Status: COMPLETED
-
NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors
NCT04550663 ·Status: UNKNOWN ·Phase: PHASE1
-
NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors
NCT06509490 ·Status: RECRUITING ·Phase: NA
-
A Preliminary Study About Unexplained Recurrent Miscarriage and Repeated Implantation Failure Patients Treated With Low-dose Lymphocyte Immunotherapy
NCT03081325 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Cytokine Regulation of Natural Killer Receptors in Inhibiting Activated T Cell Function
NCT00173290 ·Status: UNKNOWN
-
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
NCT03354390 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1