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Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History

NCT06821685 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2025-11-17

No results posted yet for this study

Summary

The aim of this study is preliminary exploration of the effectiveness and duration of autologous decidual-like NK cells therapy in improving uterine NK cells dysfunction.

Conditions

  • Abortion, Habitual
  • Infertility Unexplained
  • Embryo Implantation
  • Pre-Eclampsia

Interventions

BIOLOGICAL

autologous decidual-like NK cells

intrauterine infusion

Sponsors & Collaborators

  • The University of Science and Technology of China

    collaborator OTHER

  • The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

    lead OTHER

Principal Investigators

  • Yali Hu · The Affiliated Drum Tower Hospital of Nanjing University

  • Hui Zhu · The Affiliated Drum Tower Hospital of Nanjing University

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
22 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-13
Primary Completion
2027-07-31
Completion
2027-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06821685 on ClinicalTrials.gov