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Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure

NCT07230574 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 159

Last updated 2025-11-17

No results posted yet for this study

Summary

The aim of this study is to verify the efficacy of in vitro induction of autologous decidual-like NK cells therapy for reproductive failure associated with uterine NK cells abnormalities.

Conditions

  • Abortion, Missed
  • Infertility Unexplained
  • Reproductive Disorder

Interventions

BIOLOGICAL

NK cell perfusion group

Completing two rounds of NK cell therapy

Sponsors & Collaborators

  • The University of Science and Technology of China

    collaborator OTHER

  • Sir Run Run Shaw Hospital

    collaborator OTHER

  • Second Affiliated Hospital of Soochow University

    collaborator OTHER

  • The First Affiliated Hospital of Anhui Medical University

    collaborator OTHER

  • The First Affiliated Hospital of University of Science and Technology of China

    collaborator OTHER

  • The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

    lead OTHER

Principal Investigators

  • Yali Hu · The Affiliated Drum Tower Hospital of Nanjing University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
22 Years
Max Age
38 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-30
Primary Completion
2028-09-30
Completion
2028-09-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07230574 on ClinicalTrials.gov