Cytokine Regulation of Natural Killer Receptors in Inhibiting Activated T Cell Function
NCT00173290 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2008-06-03
Summary
In this study proposal, the investigators will extend their previous studies and examine the kinetic cytotoxic activity with concordant expression of inhibitory natural killer (NK) receptors (iNKR) on activated T cells. The inhibitory role of cytokines will be defined by utilizing the investigators' previously established models of mixed lymphocytes and tumor cells coculture to analyze the expression and activity of cytokines involved in the regulation of iNKRs on cancer-encountered T cells.
Conditions
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Bor-Ching Sheu, MD, PhD · Department of Obstetrics and Gynecology, National Taiwan University Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-07-31
- Completion
- 2006-12-31
Countries
- Taiwan
Study Locations
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