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Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain

NCT04035330 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2019-07-29

No results posted yet for this study

Summary

To compare the effect of using Etidronate in sodium hypochlorite versus sodium hypochlorite irrigating solution on:

* Postoperative pain in patients with necrotic pulp.
* Bacterial load reduction \& main bacterial species detected preinstrumentation and post-instrumentaion
* Periapical Matrix metalloproteinase 9 level (MMP-9) postinstrumentation and pre-obturation

Conditions

  • Necrotic Pulp

Interventions

COMBINATION_PRODUCT

etidronate in sodium hypochlorite

using etidronate in sodium hypochlorite solution with a volume of 5 ml between each instrument to reach a total volume of 25 ml

COMBINATION_PRODUCT

sodium hypochlorite

irrigation with 25 ml 2.5% sodium hypochlorite . 5ml between each instrument.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Laila Z Ismail, M.Sc. · Cairo University

  • Shaimaa I Gawdat, Ph.D · Cairo University

  • Randa El boghdadi, Ph.D · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-30
Primary Completion
2021-03-31
Completion
2021-09-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04035330 on ClinicalTrials.gov