Effect of Wet and Overwet Dentin on the Clinical Performance of Two Universal Adhesive Systems

Summary

The aim of this study will be to evaluate the effect of wet and overwet dentin on the long-term clinical performance of two universal adhesive systems used as etch-and-rinse application mode in non-carious cervical lesions (NCCLs).

Materials \& Methods: 200 restorations will be randomly placed in 50 subjects according to the following groups (n=50): AMP-wet (Ambar Universal APS Plus adhesive on wet dentin); AMP-overwet (Ambar Universal APS Plus adhesive on oversaturated dentin); PBA-wet (Prime\&Bond Active adhesive on wet dentin); PBA-overwet (Prime\&Bond Active adhesive on oversaturated dentin). For all groups, the enamel and dentin will be etched for 15s. All groups will be light-cured for 10s/1,000 mW/cm2. A resin composite will be placed by applying three increments and each one was light cured for 20s/1,000 mW/cm2. The restorations will be finished immediately with fine diamond burs and spiral polishers. The restorations will be evaluated at baseline and after 6 months by using the FDI criteria. The following outcomes will be evaluated: retention, marginal staining, marginal adaptation, post-operative sensitivity and recurrence of caries. The differences among the groups will be calculated using Friedman repeated measures analysis of variance rank (α = 0.05).

Conditions

• Non-carious Cervical Lesions

Interventions

PROCEDURE

Dentin Wet

Composite resin restorations of non-carious cervical lesions will be performed with an adhesive on wet dentin in the etch-and-rinse application strategy.

PROCEDURE

Dentin Overwet

Composite resin restorations of non-carious cervical lesions will be performed with an adhesive on overwet dentin in the etch-and-rinse application strategy.

DEVICE

Ambar Universal APS Plus; FGM

Composite resin restorations of non-carious cervical lesions will be performed with an universal adhesive

DEVICE

Prime&Bond Active; Dentsply Sirona

Composite resin restorations of non-carious cervical lesions will be performed with an universal adhesive

Sponsors & Collaborators

• Universidade Estadual de Ponta Grossa

  collaborator OTHER

• Universidad de los Andes, Chile

  lead OTHER

Principal Investigators

• Mario Gutierrez, PhD · Universidad de los Andes, Chile

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

99 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-01-06

Primary Completion

2025-03-03

Completion

2025-03-10

Countries

• Chile

Study Locations