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The Influence of Local Antibiotic Therapy on the Outcomes Following Periodontal Regeneration Procedures.

NCT07027137 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-06-18

No results posted yet for this study

Summary

Assessmnet of the influence of local antibiotic therapy on the clinical, radiological, microbiological parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) following periodontal regeneration procedures in patients with periodontitis.

Conditions

  • Periodontitis
  • Periodontal Diseases

Interventions

DRUG

SRP+ANB+SURG

SRP (scaling and root planing) with ANB (local antibiotic application- 10%doxycycline) and SURG (regeneration procedure according to MIST/M-MIST)

PROCEDURE

SRP+SURG

SRP (scaling and root planing) and SURG (regeneration procedure according to MIST/M-MIST)

Sponsors & Collaborators

  • Medical University of Bialystok

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-01
Primary Completion
2025-12-30
Completion
2025-12-30

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07027137 on ClinicalTrials.gov