Biomarkers and Early Alzheimer's Disease
NCT00094952 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80
Last updated 2009-09-18
Summary
The main goal of this project is to use imaging and biomarkers to identify cognitively normal elderly people who are at increased risk for developing mild cognitive impairment (MCI). MCI is the earliest clinically detectable evidence for brain changes due to Alzheimer's disease (AD). The second goal of this project is to describe the inter-relationships among anatomical biomarkers, cerebrospinal fluid biomarkers, and cognition measures in those elderly people who develop MCI.
Conditions
Sponsors & Collaborators
-
National Institute on Aging (NIA)
lead NIH
Principal Investigators
-
Mony J. de Leon, Ed.D. · Center for Brain Health, Silberstein Institute
Eligibility
- Min Age
- 60 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2003-04-30
- Completion
- 2008-03-31
Countries
- United States
Study Locations
More Related Trials
-
Alzheimer's Disease Neuroimaging Initiative Grand Opportunity
NCT01078636 ·Status: COMPLETED
-
ADNI: Alzheimer's Disease Neuroimaging Initiative
NCT00106899 ·Status: COMPLETED
-
Biomarker Study for Alzheimer's Disease
NCT02472899 ·Status: COMPLETED
-
Study on Biomarkers for Early Diagnosis of Alzheimer's Disease
NCT04575337 ·Status: RECRUITING
-
Detection of AD Biomarkers in Tear Fluid
NCT04620902 ·Status: COMPLETED
-
Biomarkers for Monitoring Dementia Progression
NCT06855368 ·Status: RECRUITING
-
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
NCT06584357 ·Status: RECRUITING
-
Blood Biomarker of Alzheimer's Disease (AD)
NCT03340571 ·Status: COMPLETED
-
Brain Connectivity Marker for Alzheimer's Disease
NCT06874231 ·Status: RECRUITING
-
New Proteins in Body Fluids as Potential Biomarker for Alzheimer's Disease: a Pilot Study
NCT01773915 ·Status: UNKNOWN
-
Alzheimer"s Imaging Biomarkers in Obesity
NCT05077579 ·Status: RECRUITING
-
Early Diagnosis of Alzheimer's Disease: Clinical, Neuropsychological and Neuroimaging Follow-up of a Cohort of Patients With an Isolated Memory Impairment
NCT00684281 ·Status: COMPLETED ·Phase: NA
-
Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia
NCT06534658 ·Status: RECRUITING
-
New CSF Biomarkers for Alzheimer's Disease
NCT03621839 ·Status: RECRUITING
-
Alzheimer's Disease Multinuclear Imaging Neuro-Enhanced Resolution (AD-MINER)
NCT07089303 ·Status: RECRUITING
-
Novel Dementia Biomarkers
NCT04427436 ·Status: UNKNOWN
-
MR Elastography of Cognitive Impairment
NCT06029114 ·Status: ENROLLING_BY_INVITATION
-
Using Neuroimaging to Early Diagnose Alzheimer's Disease Through Hippocampal Atrophy Assessment
NCT06965816 ·Status: COMPLETED
-
Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
NCT06561906 ·Status: RECRUITING
-
Multi-modality MRI Study on Prediction for Mild Cognitive Impairment Conversion
NCT02353884 ·Status: COMPLETED
-
Developing a New EEG Method for the Early Diagnosis of Dementia
NCT02426398 ·Status: RECRUITING
-
Multi-modal Neuroimaging in Alzheimer's Disease IMAP+
NCT01638949 ·Status: COMPLETED ·Phase: NA
-
Multi-modality MRI Study on Differences in Conversion of aMCI Patients With APOEε4 to AD
NCT02225964 ·Status: COMPLETED
-
Amyloid Plaque and Tangle Imaging in Aging and Dementia
NCT00355498 ·Status: COMPLETED
-
Development of an EEG Diagnostic for Alzheimer's Disease
NCT04954183 ·Status: COMPLETED