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Retrograde Versus Antegrade Perfusion in Low-Moderate Hypothermia for Aortic Arch Surgery

NCT06986967 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-08-15

No results posted yet for this study

Summary

The purpose of this study is to compare brain function after surgical circulatory arrest using either antegrade perfusion or retrograde perfusion.

Conditions

  • Brain Function
  • Hemiarch Cardiac Procedure

Interventions

PROCEDURE

Antegrade Perfusion

Procedure in which the surgeon accesses one of two arteries that branch off from the aorta to provide blood to the brain.

PROCEDURE

Retrograde Perfusion

Procedure in which the surgeon accesses the superior vena cava to supply blood to the brain.

Sponsors & Collaborators

Principal Investigators

  • Joseph Mathew, M.D. · Duke University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-18
Primary Completion
2026-12-31
Completion
2027-03-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06986967 on ClinicalTrials.gov