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Cerebral Autoregulation Monitoring During Cardiac Surgery

NCT00981474 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 460

Last updated 2021-03-02

Study results available
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Summary

Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life. New strategies of care are needed to avoid rising complications for the growing number of aged patients undergoing cardiac surgery. This study will evaluate novel methods for reducing brain injury during surgery from inadequate brain blood flow using techniques that could be widely employed.

Conditions

  • Thoracic Surgery
  • Cardiopulmonary Bypass

Interventions

DRUG

blood pressure maintenance based on cerebral blood flow autoregulation measurement

Blood pressure lowered or raised

DEVICE

Control group

Institutional standard of care.

Sponsors & Collaborators

Principal Investigators

  • Charles Hogue, MD · Northwestern University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-01
Primary Completion
2020-02-04
Completion
2020-02-28
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00981474 on ClinicalTrials.gov