A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.

Summary

By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine the optimal hypothermic circulatory arrest strategy for aortic surgery.

Conditions

• Morality
• Hypothermic Circulatory Arrest Time
• Aortic-cross Clamping Time
• Cardiopulmonary Bypass Time
• Operation Time
• Re-Thoracotomy
• ICU Stay
• Mechanical Ventilation Time
• Blood Transfusion
• Neurological Disorder
• Dialysis
• Aneurysm
• Endoleak
• Hospital Stay

Interventions

PROCEDURE

the temperature of hypothermic circulatory arrest

Different temperature (mild 30 degree or moderate 25 degree) employed during the hypothermic circulatory arrest on aortic surgery.

Sponsors & Collaborators

• Jie He.MD

  collaborator UNKNOWN

• Shihao Cai.MD

  collaborator UNKNOWN

• Wenda Gu.PhD

  collaborator UNKNOWN

• Haijiang Guo.PhD

  collaborator UNKNOWN

• Liang Hong. MD

  collaborator UNKNOWN

• Ruixing Fan.PhD

  collaborator UNKNOWN

• Jingsong Huang.PhD

  collaborator UNKNOWN

• Tucheng Sun.MD

  collaborator UNKNOWN

• Jihai Peng.MD

  collaborator UNKNOWN

• Xiaoping Fan. MD

  lead OTHER

Principal Investigators

• Xiaoping Fan, PhD · Guangdong General Hosiptal

• Jie He, MD · Guangdong General Hosiptal

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-08-03

Primary Completion

2020-02-15

Completion

2020-12-15

Countries

• China

Study Locations