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The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study

NCT06839300 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 260

Last updated 2026-05-05

No results posted yet for this study

Summary

To determine the accuracy of serum NF-L and GFAP levels (ie the biomarkers) at different time points postinjury for predicting the severity of neurologic impairment at 6 months postinjury as either motor complete (AIS grade A/B) or motor incomplete (AIS grade C/D) a group of patients who suffer traumatic spinal fracture and/or dislocation of the spinal column but without neurologic injury will be enrolled as non-SCI spine trauma control participants.

Conditions

Sponsors & Collaborators

  • AO Foundation, AO Spine

    lead OTHER

Principal Investigators

  • Brian Kwon, MD, PhD, FRCSC · The University of British Columbia

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-09
Primary Completion
2029-12-01
Completion
2029-12-01

Countries

  • United States
  • Australia
  • Brazil
  • Chile
  • Germany
  • India
  • New Zealand
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06839300 on ClinicalTrials.gov