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Biomarkers of Spontaneous Recovery From Traumatic Spinal Cord Injury

NCT02731027 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42

Last updated 2020-11-13

No results posted yet for this study

Summary

The purpose of the study is to profile biochemical responses and measure functional recovery in parallel, throughout the 1st year after spinal cord injury (SCI), within the same participants. These responses and recovery will be evaluated in samples from people who have had a spinal cord injury due to trauma (e.g. car accident or a fall) within the first year after SCI. Specifically, the investigators will test the hypothesis that a subset of inflammatory biomarkers correlate inversely with functional recovery. The investigators will use these data to build a predictive model of functional recovery after SCI that incorporates biomarkers that can be easily quantified in the clinic.

Total anticipated enrollment will be 100 participants with SCI across three different sites (Northwell Health System (NY), The Kessler Institute for Rehabilitation (NJ), University of Louisville (KY) and may enroll up to 30 participants without SCI.

Conditions

  • Spinal Cord Injury

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • New York State Department of Health

    collaborator OTHER_GOV

  • University of Louisville

    collaborator OTHER

  • Kessler Foundation

    collaborator OTHER

  • Thomas Jefferson University

    collaborator OTHER

  • University of British Columbia

    collaborator OTHER

  • Ohio State University

    collaborator OTHER

  • Northwell Health

    lead OTHER

Principal Investigators

  • Ona Bloom, Ph.D. · Northwell Health System

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2020-09-30
Completion
2020-09-30

Countries

  • United States
  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02731027 on ClinicalTrials.gov