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The Neuroinflammatory Response and Biomarkers in Acute Traumatic Spinal Cord Injury

NCT03505463 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2020-11-13

No results posted yet for this study

Summary

The study is a prospective cohort study designed to assess the diagnostic and prognostic potential of biomarker measurement in acute traumatic spinal cord injury (TSCI), and to examine the neuroinflammatory response to acute TSCI.

Conditions

  • Spinal Cord Injury, Acute

Interventions

OTHER

Blood samples

Three blood samples will be collected from the injured participants. The assessment points are \<72 hours, 7 days and 365 days post-injury. One blood sample will be collected from the healthy participants. The collection will be performed as part of clinical diagnostic at the Department of Neurology at Aarhus University Hospital. Laboratory analysis of the collected samples comprise Flow Cytometry and assay techniques.

OTHER

Cerebrospinal fluid sample

Three cerebrospinal fluid samples will be collected from the injured participants. The assessment points are \<72 hours, 7 days and 365 days post-injury. The collected samples will be analysed by Flow Cytometry and assay techniques. One cerebrospinal fluid sample will be collected from the healthy participants. The collection will be performed as part of clinical diagnostic at the Department of Neurology at Aarhus University Hospital. Laboratory analysis of the collected samples comprise Flow Cytometry and assay techniques.

OTHER

Clinical examination

Clinical examinations will be performed at \<72 hours, 7 days and 365 days post-injury.

Sponsors & Collaborators

  • Aarhus University Hospital

    collaborator OTHER

  • Spinal Cord Injury Centre of Western Denmark

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-05-01
Primary Completion
2020-12-01
Completion
2020-12-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03505463 on ClinicalTrials.gov