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The Impact of Through-and-through Guidewire on Percutaneous Nephrolithotomy

NCT06837883 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 106

Last updated 2025-02-20

No results posted yet for this study

Summary

The aim to the study is to investigate the impact of combined retrograde and antegrade insertion of a through-and-through guidewire during percutaneous nephrolithotomy (PCNL). Adult patients with complex renal stones (Guy's stone score III, IV) were ranomized between standard PCNL (control group) and PCNL with comibined retrograde and antegrade inserted through-and-through guidewire (study group). This modification initially involves the retrograde insertion of an additional guidewire beside the ureteral catheter. After percutaneous puncture and dilation of the tract, the guidewire is pulled antegrade through the renal access, using either ureteroscopy or nephroscopy to secure the tract throughout the procedure.The primary outcome is to compare the initial stone free rate (SFR) between both groups. The secondary outcome is to compare both groups as regard operative time, fluorscopy time, number of tracts, haemoglobin drop, blood transfusion and major complications accoridng to Clavien-Dindo (CD) system. Success is defined as presence of insignificant residual less than 4 mm.

Conditions

  • Nephrolithotomy, Percutaneous

Interventions

PROCEDURE

Percutaneous nephrolithotomy through and through guiedwire

In the study group, a modification in percutaneous nephrolithotomy was carried out to have through-and-through guidewire.

PROCEDURE

Standard percutaneous nephrolithotomy

Standard percutaneous nephrolithotomy without using through and through guide wire

Sponsors & Collaborators

  • South Valley University

    lead OTHER

Principal Investigators

  • Osama Mahmoud, Dr. · South Valley University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-06-01
Primary Completion
2024-06-01
Completion
2024-06-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06837883 on ClinicalTrials.gov