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Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)

NCT06806397 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2025-02-04

No results posted yet for this study

Summary

The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simple stimulus-response task several times with one healthy and one paralyzed limb at different stages of basic rehabilitation. A group of healthy, age-matched volunteers participated in the same experiment to verify the stroke-related changes. The researchers recorded fNIRS signals, muscle activity using electromyography, and heart activity using electrocardiography.

Conditions

  • Stroke
  • Stroke with Hemiparesis
  • Stroke, Ischemic

Interventions

DIAGNOSTIC_TEST

Stimulus response task

Participants were tasked with performing a finger extension exercise that required pressing buttons in response to visual stimuli. In cases where physical movement was not possible, participants were instructed to imagine performing the task while focusing on their fingers.

Sponsors & Collaborators

  • Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency of Russia

    collaborator UNKNOWN

  • Skolkovo Institute of Science and Technology

    lead OTHER

Eligibility

Min Age
35 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-26
Primary Completion
2025-01-20
Completion
2025-04-30

Countries

  • Russia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06806397 on ClinicalTrials.gov