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Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.

NCT06386627 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2024-05-23

No results posted yet for this study

Summary

The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic stimulation in people with motor impairment after stroke. Participants in the study performed a simple stimulus-response task with a healthy and a paralysed limb several times at different stages of basic rehabilitation. To compare the data, a group of healthy volunteers took part in a similar experiment. Investigators recorded cortical activity using electroencephalography and muscle activity using electromyography. After the stimulus-response task, investigators also carried out a study using transcranial magnetic stimulation to assess the integrity of corticospinal connections.

Conditions

Interventions

DIAGNOSTIC_TEST

Stimulus response task

Participants were tasked with performing a finger extension exercise that required pressing buttons in response to visual stimuli. In cases where physical movement was not possible, participants were instructed to imagine performing the task while focusing on their fingers.

DIAGNOSTIC_TEST

Transcranial magnetic stimulation

Transcranial magnetic stimulation to assess the integrity of corticospinal connections

Sponsors & Collaborators

  • Federal center of brain research and neurotechnologies, FMBA, Moscow, Russia

    collaborator UNKNOWN

  • Skolkovo Institute of Science and Technology

    lead OTHER

Eligibility

Min Age
30 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-07-01
Primary Completion
2024-03-15
Completion
2024-03-15

Countries

  • Russia

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06386627 on ClinicalTrials.gov