Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders
NCT06747000 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 80
Last updated 2025-10-01
Summary
This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications.
The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.
Conditions
- Lipid Disorders
Sponsors & Collaborators
-
The Miriam Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 69 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-07-18
- Primary Completion
- 2028-07-18
- Completion
- 2029-07-18
Countries
- United States
Study Locations
More Related Trials
-
Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions
NCT06676046 ·Status: RECRUITING
-
VLDL and LDL Particle Types as Coronary Heart Disease Risk Factors
NCT00065793 ·Status: COMPLETED
-
Advanced Lipoproptein Profiling and Cardiovascular Risk Stratification in Familial Hypercholesterolemia
NCT05066932 ·Status: UNKNOWN
-
Role of LipoprotEin(a) in CardiovascuLar Diseases and Premature Acute Coronary Syndromes - (RELACS) Study
NCT05496790 ·Status: UNKNOWN
-
Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers
NCT03038750 ·Status: TERMINATED
-
Genomic Basis of Neurodevelopmental and Brain Outcomes in Congenital Heart Disease (CHD Brain and Genes)
NCT03070197 ·Status: COMPLETED
-
Risk Burden of Lipoprotein Metabolic Gene Haplotypes
NCT00090441 ·Status: COMPLETED
-
High Density Lipoprotein Subspecies and Coronary Disease
NCT00005676 ·Status: COMPLETED
-
Vascular Disease Discovery Protocol
NCT03538639 ·Status: RECRUITING
-
Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk
NCT00613158 ·Status: COMPLETED
-
Genomic Dissection of a QTL Affecting the Lipid Profile
NCT00064688 ·Status: WITHDRAWN
-
Familial Hyperlipidemia Family Registry
NCT05814419 ·Status: COMPLETED
-
Improving Cardiovascular Treatment Approaches Among Minorities
NCT00101478 ·Status: COMPLETED
-
Evaluation of Cascade Screening for Elevated Lipoprotein(a)
NCT06157983 ·Status: ACTIVE_NOT_RECRUITING
-
Lipid Research Clinics Population Studies
NCT00005128 ·Status: COMPLETED
-
Continuation of the nuMoM2b Heart Health Study
NCT05472597 ·Status: ENROLLING_BY_INVITATION
-
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux
NCT04061018 ·Status: COMPLETED
-
Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease
NCT00013975 ·Status: COMPLETED
-
Diet, Genetics, and CVD Risk Factor Response in Blacks
NCT00079703 ·Status: COMPLETED
-
Gene-Specific Responses to Exercise in Discordant Twins
NCT00083837 ·Status: COMPLETED
-
Lipoprotein(a) in Patients With Cardiovascular Disease (CVD)
NCT03887520 ·Status: COMPLETED ·Phase: NA
-
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health
NCT05819814 ·Status: RECRUITING ·Phase: NA
-
Lipoprotein (a) and Vascular Regenerative Cell Content
NCT06626659 ·Status: COMPLETED
-
Assessment of Lipoprotein(a) and Endogenous Fibrinolysis in Atherosclerotic Cardiovascular Disease/Aortic Valve Disease
NCT06126367 ·Status: RECRUITING
-
Mitral Valve Prolapse (MVP) - France Study
NCT00799565 ·Status: COMPLETED ·Phase: NA