Brain Health in Midlife
NCT06640842 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24
Last updated 2025-06-29
Summary
The purpose of this study is to learn if hypertensive disorders during pregnancy affects brain health in midlife.
Conditions
- Brain Health
- Gestational Hypertension
- Alzheimer Disease
- Dementia
- Cardiovascular Diseases
- Pregnancy Related
- Pre-Eclampsia
Interventions
- DIAGNOSTIC_TEST
-
A combination of various test and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy in brain health in midlife.
Participants will be asked to complete a blood draw, 5-lead ECG, MRI, a series of cognitive assessments, dietary assessments, monitor sleep and physical activity and DXA scan.
Sponsors & Collaborators
-
National Institute on Aging (NIA)
collaborator NIH -
University of Kansas Medical Center
lead OTHER
Principal Investigators
-
Holly R Hull, PhD · University of Kansas Medical Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 54 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-09-23
- Primary Completion
- 2025-06-13
- Completion
- 2025-06-13
Countries
- United States
Study Locations
More Related Trials
-
The Effects of Sex Hormones on Cognition and Mood in Older Adults
NCT00000175 ·Status: TERMINATED ·Phase: NA
-
Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement
NCT00001412 ·Status: COMPLETED
-
Age-Related Changes in Stress Hormone Regulation
NCT00018369 ·Status: COMPLETED
-
The Effects of the Female Hormones on Cerebral Perfusion
NCT03299179 ·Status: RECRUITING
-
Study on Allopregnanolone and Depression in Women Across the Menopause Transition
NCT06238700 ·Status: RECRUITING ·Phase: NA
-
Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression
NCT00001479 ·Status: COMPLETED
-
Impact of Hot Flashes on Sleep and Mood Disturbance
NCT01116401 ·Status: COMPLETED ·Phase: PHASE4
-
Brain Fog and Life Quality in Menopause
NCT06978218 ·Status: COMPLETED
-
The Effects of Reproductive Hormones on Mood and Behavior
NCT00001322 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Brain Blood Flow Responses to Stress: Sex Differences
NCT06253702 ·Status: COMPLETED ·Phase: PHASE4
-
Dynamics of Leptin and Endocrine Function
NCT00001543 ·Status: COMPLETED
-
Perimenopause-Related Mood and Behavioral Disorders
NCT00001231 ·Status: COMPLETED
-
Hormone Deficiency After Brain Injury During Combat
NCT01666964 ·Status: UNKNOWN
-
Neuroendocrine Dysfunction in Traumatic Brain Injury: Correlation With Cognitive Dysfunction and Repair
NCT00336726 ·Status: TERMINATED
-
The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
NCT00001232 ·Status: COMPLETED
-
A Treatment Study for Premenstrual Syndrome (PMS)
NCT00001259 ·Status: COMPLETED ·Phase: PHASE1
-
The Potential Role of Testosterone on Target Organ Damage in Postmenopausal Hypertensive Women
NCT03451747 ·Status: UNKNOWN
-
Estrogen Deficiency and Cardiovascular Disease in Premenopausal Women
NCT00572858 ·Status: COMPLETED
-
Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones
NCT00562367 ·Status: COMPLETED ·Phase: NA
-
Effect of Hydrocortisone on the Brain
NCT00055003 ·Status: COMPLETED
-
Study on Allopregnanolone and Depression in Perimenopausal Women
NCT05329779 ·Status: TERMINATED ·Phase: PHASE4
-
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
NCT03505905 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effects of Progesterone on IV Nicotine Induced Changes on BOLD fMRI Signal, Hormones and Subjective Ratings of Stimulant Drugs
NCT01589068 ·Status: WITHDRAWN ·Phase: NA
-
Dutasteride to Treat Women With Menstrually Related Mood Disorders
NCT00082043 ·Status: COMPLETED ·Phase: PHASE1
-
Perimenopausal Effects of Estradiol on Reward Responsiveness
NCT02255175 ·Status: COMPLETED ·Phase: PHASE4