Brain Fog and Life Quality in Menopause
NCT06978218 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 122
Last updated 2025-08-11
Summary
This clinical study aims to investigate cognitive changes in women undergoing the menopausal transition, with a specific focus on the prevalence, characteristics, and impact of brain fog. The research will assess how declining estrogen levels influence cognitive domains such as memory, attention, and executive function across different menopausal stages (perimenopause, menopause, and postmenopause). Through a comparative and observational design, the study will evaluate the relationship between subjective cognitive complaints and menopause-specific quality of life. Findings are expected to inform the development of non-pharmacological strategies-such as lifestyle modifications and cognitive health interventions-to mitigate cognitive decline and improve overall well-being in midlife women.
Conditions
- Menopause
- Cognitive Dysfunction
- Memory Disorders
- Quality of Life
- Women's Health
- Perimenopausal Disorder
- Postmenopausal Symptoms
Sponsors & Collaborators
-
Merve Coskun
lead OTHER
Principal Investigators
-
Merve Coşkun, Asst. Prof. · Acibadem University
Eligibility
- Min Age
- 40 Years
- Max Age
- 60 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-05-08
- Primary Completion
- 2025-07-16
- Completion
- 2025-07-16
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen
NCT06358014 ·Status: RECRUITING ·Phase: NA
-
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
NCT00113867 ·Status: COMPLETED
-
Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder
NCT00626340 ·Status: COMPLETED ·Phase: PHASE4
-
Sleeping Through Menopause
NCT06306404 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Sexual Functions and Marital Adjustment for Spouses in Menopause
NCT05338645 ·Status: COMPLETED
-
Estrogen and Serotonin on Changing Brain Chemistry
NCT01208324 ·Status: COMPLETED ·Phase: NA
-
Perimenopausal Effects of Estradiol on Reward Responsiveness
NCT02255175 ·Status: COMPLETED ·Phase: PHASE4
-
Estrogen and Perimenopausal Depression
NCT00229450 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Menstruation on Food Preference and Balance
NCT05821439 ·Status: UNKNOWN
-
Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older Individuals
NCT01988610 ·Status: COMPLETED ·Phase: PHASE1
-
Depressive Symptoms and Subjective Stress in the Course of the Menstrual Cycle - an Ambulatory Assessment Study.
NCT04086316 ·Status: COMPLETED
-
Melatonin Use in Patients With Climacterious Symptoms in the Perimenopause
NCT06192641 ·Status: COMPLETED ·Phase: PHASE2
-
Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction
NCT06678880 ·Status: RECRUITING ·Phase: NA
-
Effects of Cranial Massage in Menopausal Women
NCT03565952 ·Status: COMPLETED ·Phase: NA
-
The Effect of Menopause on Sexual Life and Depression: a Case-control Study.
NCT05312099 ·Status: COMPLETED
-
Estrogen Variability and Irritability During the Menopause Transition
NCT05388656 ·Status: COMPLETED ·Phase: PHASE4
-
Progesterone Reduces Wakefulness in Sleep EEG and Has no Effect on Cognition in Healthy Postmenopausal Women
NCT00530582 ·Status: COMPLETED ·Phase: PHASE4
-
Mental Imagery in Menstrual Cycle Phases
NCT06558266 ·Status: COMPLETED
-
How Seasons Affect Kidney Health in Post-Menopausal Females
NCT06866743 ·Status: COMPLETED
-
Brain Health in Midlife
NCT06640842 ·Status: COMPLETED
-
Sleep Quality and the Menstrual Cycle
NCT06906133 ·Status: ACTIVE_NOT_RECRUITING
-
Study on Allopregnanolone and Depression in Women Across the Menopause Transition
NCT06238700 ·Status: RECRUITING ·Phase: NA
-
Combined Hormone Replacement in Menstrually-Related Mood Disorders
NCT00005011 ·Status: COMPLETED
-
Examining the Relationship Between Hormone Therapy (HT) and Cognitive Function (The WHIMS-ECHO Study)
NCT00745056 ·Status: COMPLETED
-
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
NCT03505905 ·Status: COMPLETED ·Phase: PHASE1/PHASE2