Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
NCT06596746 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 600
Last updated 2024-09-19
Summary
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal clinical practice. Data collected from clinical evaluations, movement analysis, brain imaging, neuropsychological and electroencephalographic assessments, blood chemistry tests will be analysed to carry out statistical investigations and predictive analyses, also using artificial intelligence systems, which allow the identification of new early markers of diagnosis and prognosis of neurodegenerative diseases.
Conditions
- Neurodegenerative Diseases
- Parkinson Disease
- Synucleinopathies
- Lewy Body Disease
- Multiple System Atrophy
- Tauopathies
- Alzheimer Disease
- Corticobasal Degeneration
- Supranuclear Palsy, Progressive
- Atypical Parkinsonism
- TDP-43 Proteinopathies
- Amyotrophic Lateral Sclerosis
- Frontotemporal Lobar Degeneration
- Movement Disorders
- Cognitive Impairment
- Dementia
- Iron Overload
- Neurodegeneration With Brain Iron Accumulation (NBIA)
Interventions
- OTHER
-
Observation
In MARKERS-NDD up to 600 participants will be enrolled and followed longitudinally once identified, over the course of 1-10 years
Sponsors & Collaborators
-
IRCCS San Raffaele Roma
collaborator OTHER -
San Raffaele Telematic University
collaborator OTHER -
University of Urbino "Carlo Bo"
collaborator OTHER -
University of Cassino and Southern Lazio
collaborator UNKNOWN -
University of Roma La Sapienza
collaborator OTHER -
Politecnico di Milano
collaborator OTHER -
Casa di Cura San Raffaele Cassino
lead NETWORK
Eligibility
- Min Age
- 10 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-09
- Primary Completion
- 2034-09-09
- Completion
- 2034-09-09
Countries
- Italy
Study Locations
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