Eating Disorders Genetics Initiative 2

Summary

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Conditions

• Anorexia Nervosa
• Bulimia Nervosa
• Binge-Eating Disorder
• Avoidant Restrictive Food Intake Disorder

Interventions

OTHER

Eating disorder diagnosis group

This is an observational study, no active intervention is applied. Participants are assigned to an eating disorder diagnosis group based on their lifetime history of disordered eating behaviors and symptoms.

Sponsors & Collaborators

• Queensland Institute of Medical Research

  collaborator OTHER

• Karolinska Institutet

  collaborator OTHER

• National Institute of Mental Health (NIMH)

  collaborator NIH

• University of Otago

  collaborator OTHER

• University of Aarhus

  collaborator OTHER

• Yale University

  collaborator OTHER

• Comenzar de Nuevo, AC

  collaborator OTHER

• University of Sydney

  collaborator OTHER

• University of North Carolina, Chapel Hill

  lead OTHER

Principal Investigators

• Cynthia Bulik, PhD · University of North Carolina, Chapel Hill

Eligibility

Min Age

12 Years

Max Age

99 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-10-28

Primary Completion

2027-08-01

Completion

2027-08-01

Countries

• United States
• Australia
• Mexico
• New Zealand
• Sweden

Study Locations