MedTrace Logo

Exploring the Landscape of Somatic Mutations in Human Tissue

NCT06585800 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 1800

Last updated 2024-09-19

No results posted yet for this study

Summary

Every cell in the human body contains a blueprint of the body called the genome. Throughout life, the genome can become damaged resulting in errors (mutations) that can change the way cells behave and may result in diseases such as cancer. Examining the mutations found the genome of both normal (non-cancerous) and diseased cells can give a valuable insight into the very earliest stages of cancer development.

Comparing the number and type of mutations in different normal tissues is revealing new insights, helping us to better understand more about why cancer develops.

Conditions

  • Somatic Mutation

Interventions

OTHER

sample collection

blood and/or tissue collection

Sponsors & Collaborators

  • The Wellcome Sanger Institute

    lead OTHER

Principal Investigators

  • Mike Stratton · Wellcome Sanger Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2026-01-31
Completion
2026-01-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06585800 on ClinicalTrials.gov