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Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

NCT03027401 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2020-10-08

No results posted yet for this study

Summary

Background:

Saliva, blood, tissue, and cancer contain DNA. DNA makes the "instruction book" for the cells in the body. Cancer is caused by changes in DNA that affect cell function. Researchers want to test DNA of people with tumors. They want to look for genetic changes in tumors that could be targets for treatment. Because DNA can change as cancer changes, more testing may be done at different times.

Objectives:

To find the DNA changes in cancer that may help guide treatment. To collect samples and data to be used in future studies.

Eligibility:

People any age with cancer or a pre-cancerous tumor

Design:

* Participants will be screened with a medical history, physical exam, and blood tests. Participants will give a sample of their tumor. This is usually from a previous procedure. Participants will give a saliva or blood sample. They cannot eat, drink, smoke, or chew gum for 30 minutes before giving saliva. They will spit about 1 teaspoon of saliva into a tube.
* Some participants may have a punch biopsy instead. A small instrument will take a small piece of skin.
* Researchers will collect data from participants medical records.
* Participants will answer questions about their family health history. They will also answer questions about their views on the study, including possible unexpected results.
* Extra blood or tissue samples may be taken at other times during the participants' treatment. All samples will be saved in secure ClinOmics freezers to be used in future studies.
* Participants will be told by their doctors if any test results affect their health or their cancer treatment.

Conditions

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    lead NIH

Principal Investigators

  • Javed Khan, M.D. · National Cancer Institute (NCI)

Eligibility

Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-10
Primary Completion
2020-10-05
Completion
2020-10-05

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03027401 on ClinicalTrials.gov