Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

Summary

Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common. These can lead to high rates of depression, anxiety, and PTSD that worsen quality of life. Yet there are few effective strategies able to overcome barriers of limited access to mental health care. Even less is known about the experiences of patients from racially and ethnically minoritized populations because of they haven't been included well in past research.

To address this problem, the investigators developed Blueprint, a mobile app that coaches people to use adaptive coping skills to self-manage their symptoms. The investigators found that it reduced depression symptoms and improved quality of life compared to placebo.

To confirm these promising findings, the investigators are doing a formal test of Blueprint. The investigators will enroll 400 people who received ICU care from 4 hospitals (Duke, UCLA, Colorado, and Oregon). These patients will be randomized to receive either the Blueprint mobile app or a special Education Program mobile app the investigators developed. -both delivered through similar mobile app platforms. Our specific aims are to see which program improves symptoms better across 6 months of follow up.

This project addresses national research priorities and could advance the field with a personalizable yet population-focused therapy that could be scaled broadly and efficiently to enhance mental health equity.

Conditions

• Depression
• Anxiety
• Post-traumatic Stress Disorder
• Stress
• Worries; Pain or Disability
• Breath Shortness

Interventions

BEHAVIORAL

Blueprint

This is a mobile app-based adaptive coping skills intervention that lasts 1 month

BEHAVIORAL

Education program

This is a mobile app-based education program that lasts 1 month

Sponsors & Collaborators

• Oregon Health and Science University

  collaborator OTHER

• University of Colorado, Denver

  collaborator OTHER

• University of California, Los Angeles

  collaborator OTHER

• Duke University

  lead OTHER

Principal Investigators

• Christopher Cox · Professor of Medicine

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-10-15

Primary Completion

2027-11-15

Completion

2028-04-15

Countries

• United States

Study Locations