Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
NCT06529744 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2025-11-20
Summary
To develop a model to predict disease progression in a large cohort of patients across a variety of neurodegenerative diseases, including Mild Cognitive Impairment (MCI) and dementia due to any neurodegenerative disease, including Alzheimer's Disease (AD), Lewy Body Disease (LBD), Vascular Disease (VaD) and Frontotemporal lobar degeneration (FTLD).
Conditions
- Dementia
- Alzheimer Disease
- Dementia With Lewy Bodies
- Vascular Dementia
- Frontotemporal Dementia
- Mild Cognitive Impairment
- Corticobasal Syndrome
- Progressive Supranuclear Palsy
- Parkinson Disease
- Primary Progressive Aphasia
Sponsors & Collaborators
-
Sunnybrook Health Sciences Centre
collaborator OTHER -
Baycrest
collaborator OTHER -
Centre for Addiction and Mental Health
collaborator OTHER -
Toronto Dementia Research Alliance (TDRA)
collaborator UNKNOWN -
University of Toronto
collaborator OTHER -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
Maria C Tartaglia, M.D. · Toronto Western Hospital, UHN; Tanz CRND
Eligibility
- Min Age
- 30 Years
- Max Age
- 95 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-11-11
- Primary Completion
- 2026-11-30
- Completion
- 2027-11-30
Countries
- Canada
Study Locations
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