Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

NCT06529744 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2025-11-20

No results posted yet for this study

Summary

To develop a model to predict disease progression in a large cohort of patients across a variety of neurodegenerative diseases, including Mild Cognitive Impairment (MCI) and dementia due to any neurodegenerative disease, including Alzheimer's Disease (AD), Lewy Body Disease (LBD), Vascular Disease (VaD) and Frontotemporal lobar degeneration (FTLD).

Conditions

Sponsors & Collaborators

  • Sunnybrook Health Sciences Centre

    collaborator OTHER
  • Baycrest

    collaborator OTHER
  • Centre for Addiction and Mental Health

    collaborator OTHER
  • Toronto Dementia Research Alliance (TDRA)

    collaborator UNKNOWN
  • University of Toronto

    collaborator OTHER
  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Maria C Tartaglia, M.D. · Toronto Western Hospital, UHN; Tanz CRND

Eligibility

Min Age
30 Years
Max Age
95 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-11
Primary Completion
2026-11-30
Completion
2027-11-30

Countries

  • Canada

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06529744 on ClinicalTrials.gov