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DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia

NCT05768425 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2023-10-10

No results posted yet for this study

Summary

This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.

Conditions

Interventions

DIAGNOSTIC_TEST

Real-time quaking-induced conversion (RT-QuIC)

RT-QuIC measures the ability of alpha-synuclein (aSyn) to misfold other aSyn proteins and is an amplification technique.

DIAGNOSTIC_TEST

Cognitive test

Minimal Mental State examination (MMSE), Montreal Cognitive Assessment (MoCA)

DIAGNOSTIC_TEST

Motor examination

Unified Parkinsons Rating Scale (UPDRS)

Sponsors & Collaborators

  • Danish Reference Center for Prion Diseases, Rigshospitalet

    collaborator UNKNOWN

  • Department of Otorhinolaryngology, Head and Neck Surgery & Audiology, Rigshospitalet

    collaborator UNKNOWN

  • Danish Dementia Research Centre

    lead NETWORK

Principal Investigators

  • Oskar McWilliam · Danish Dementia Research Centre, Rigshospitalet, Capital Region

  • Kristian S Frederiksen · Danish Dementia Research Centre, Rigshospitalet, Capital Region

  • Anja H Simmonsen · Danish Dementia Research Centre, Rigshospitalet, Capital Region

  • Steen G Hasselbalch · Danish Dementia Research Centre, Rigshospitalet, Capital Region

  • Gunhild Waldemar · Danish Dementia Research Centre, Rigshospitalet, Capital Region

  • Marie Brunn · Danish Dementia Research Centre, Rigshospitalet, Capital Region

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-01
Primary Completion
2032-12-31
Completion
2032-12-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05768425 on ClinicalTrials.gov