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Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method

NCT06471244 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-05-28

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are:

* Does the testbed better localize brain sources for finger movement?
* Does the testbed better localize brain sources for median nerve stimulation?
* Does the testbed better localize brain sources for speech processing?
* Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators.

Participants will:

* Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation
* Undergo three different EEG tests
* Undergo three different MEG tests

Conditions

  • Healthy

Interventions

OTHER

Finger tapping

The volunteer is tapping with his/her right hand index finger.

OTHER

Median nerve stimulation

Electrical pulses are applied at the wrist to the median nerve.

OTHER

Speech processing

German sentences are played to the volunteers and the volunteers have to fulfill a semantic task.

Sponsors & Collaborators

  • Technische Universität Ilmenau

    collaborator UNKNOWN

  • Max Planck Institute for Human Cognitive and Brain Sciences

    collaborator OTHER

  • Worcester Polytechnic Institute

    lead OTHER

Principal Investigators

  • Sergey N Makaroff, PhD · Worcester Polytechnic Institute

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2027-04-01
Completion
2027-04-01

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06471244 on ClinicalTrials.gov