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Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy

NCT04788628 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2025-11-17

No results posted yet for this study

Summary

This study will investigate the role of coordinated brain rhythms during sleep in memory consolidation and determine whether playing precisely timed brief bursts of noise can enhance these rhythms and improve memory in epilepsy inpatients with implanted hippocampal electrodes.

Conditions

Interventions

OTHER

Baseline

Hippocampal and scalp EEG monitoring during overnight sleep

OTHER

Motor procedural memory task

Training on the finger tapping MST prior to monitored overnight sleep with MST testing the following morning

OTHER

Motor procedural memory task plus auditory stimulation

Training on the finger tapping MST prior to monitored overnight sleep that includes auditory stimulation, with MST testing the following morning

Sponsors & Collaborators

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Dara Manoach, PhD · Professor

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
12 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-21
Primary Completion
2026-03-31
Completion
2026-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04788628 on ClinicalTrials.gov