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Characterization of Left Atrial Substrate in Patients With Ventricular Arrhythmias

NCT06425822 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2024-05-22

No results posted yet for this study

Summary

The goal of this observational study is to analyze the characteristics of left atrial electroanatomical maps in patients without a history of atrial fibrillation but with a high clinical risk of developing it, as indicated by the presence of structural heart disease or a CHA2DS2-VASc score ≥ 2 points. The study cohort will be compared to a historical cohort of patients with diagnosed atrial fibrillation in a propensity-matched fashion.

The main questions it aims to answer are:

* Are the left atrial electroanatomical changes a consequence or a precursor to the development of atrial fibrillation?
* Are the left atrial electroanatomical findings different between patients with atrial fibrillation and those at high risk of developing it?
* What is the prognostic impact of left atrial pathologic changes in patients without diagnosed atrial fibrillation in terms of cardiovascular outcomes?

Conditions

  • Atrial Remodeling

Interventions

DIAGNOSTIC_TEST

Left atrial electroanatomical mapping

Left atrial electroanatomical mapping (substrate and functional mapping)

Sponsors & Collaborators

  • Universitair Ziekenhuis Brussel

    lead OTHER

Principal Investigators

  • Andrea Sarkozy, MD, PhD · Universitair Ziekenhuis Brussel

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-08
Primary Completion
2025-10-31
Completion
2027-10-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06425822 on ClinicalTrials.gov