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Predictors of Risk in Left Ventricular Non-Compaction

NCT06024759 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-11-01

No results posted yet for this study

Summary

The goal of this study is to learn more about the risk factors associated with left ventricular non-compaction (LVNC) and the predictors of adverse outcomes associated with LVNC. The main questions this study aims to answer are as follows.

* Are there any genetic mutations that impact the risk of LVNC patients developing ventricular arrhythmias?
* Does LV myocardial strain increase risk stratification in the LVNC population with or without genetic mutations?
* What are some of the determinants that cause LV dysfunction in LVNC?
* What are other risk stratifiers (ex. premature ventricular contraction (PVC) burden on Holter, non-sustained ventricular tachycardia (NSVT) on stress test) that lead to an outcome of ICD implantation?

Participants will have their medical records accessed annually for a span of ten years, either prospectively or retrospectively depending on whether they are being actively followed by physicians at the Inherited Arrhythmia Clinic or not, to evaluate LVNC progression over time. This data will be stored in a large clinical registry with the London Heart Rhythm Program at the London Health Sciences Centre, University Hospital Campus.

Conditions

  • Left Ventricular Noncompaction

Sponsors & Collaborators

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2033-08-01
Completion
2033-08-01

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06024759 on ClinicalTrials.gov