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G3P-01 in Volunteers With Elevated Galectin-3

NCT06398821 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2024-08-09

No results posted yet for this study

Summary

G3P-01 is an investigational pectin extracted, enriched and purified from commercial squash puree intended for human consumption. Pectins are an important constituent of fruits and vegetables, and health benefits are attributed to its intake. Some of the health benefits of pectins are attributed to inhibition of galectin-3. This study investigates if 30-days of G3P-01 intake in individuals with elevated galectin-3 induces biomarker changes that can be attributed to target engagement. Participants will be randomized into four groups (placebo, 100mg, 250mg and 1000mg G3P-01).

Conditions

  • Galectin 3
  • Healthy Aging

Interventions

DIETARY_SUPPLEMENT

G3P-01

Nutritional supplement to promote healthy aging

DIETARY_SUPPLEMENT

Placebo

Placebo

Sponsors & Collaborators

  • G3 Pharmaceuticals

    collaborator UNKNOWN

  • General Practitioners Research Institute

    lead NETWORK

Principal Investigators

  • J WH Kocks, MD, PhD · General Practitioners Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-18
Primary Completion
2024-04-16
Completion
2024-05-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06398821 on ClinicalTrials.gov