Effect of Probiotics on Blood Pressure Management
NCT03973710 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2022-05-09
Summary
Dysbiosis of gut microbiota has been reported to be involved in the development and progression of hypertension in both humans and animal models. Probiotics have been reported to have ameliorative effects in murine models. However, whether probiotics could help alleviate hypertension in adults remain obscure.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Lactobacillus paracasei dietary supplement
a commercial probiotic dietary supplement
- DIETARY_SUPPLEMENT
-
Placebo controls
placebo with a similar appearance to probiotics supplement
Sponsors & Collaborators
-
Sun Yat-sen University
lead OTHER
Principal Investigators
-
Min Xia, PhD · Sun Yat-sen University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-06-03
- Primary Completion
- 2023-03-31
- Completion
- 2023-12-31
Countries
- China
Study Locations
More Related Trials
-
Effect of Probiotics on Cardiometabolic Health
NCT05005754 ·Status: COMPLETED ·Phase: NA
-
Probiotics for Liver Cirrhosis With Portal Hypertension
NCT01598064 ·Status: COMPLETED ·Phase: NA
-
Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation
NCT04667884 ·Status: COMPLETED ·Phase: NA
-
Determination of the Safety and Efficacy of Two Probiotic Strains
NCT06466174 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Probiotics Alleviate Functional Constipation in Adults
NCT06879587 ·Status: COMPLETED ·Phase: NA
-
The Effect of Feeding Infant Formula Containing Prebiotics and/or Probiotics
NCT02948114 ·Status: TERMINATED ·Phase: NA
-
Effect of Probiotic on Depression
NCT04567147 ·Status: COMPLETED ·Phase: PHASE1
-
The Impact of Compound Probiotic Freeze-dried Powder on Enhancing Gastrointestinal Health
NCT07025798 ·Status: COMPLETED ·Phase: NA
-
Effectiveness and Safety of Probiotics in Relieving Anxiety and Depression
NCT06629441 ·Status: COMPLETED ·Phase: NA
-
The Efficacy and Mechanisms of Oral Probiotics in Preventing Necrotizing Enterocolitis
NCT02552706 ·Status: UNKNOWN ·Phase: NA
-
Research on the Role of Compound Probiotic Freeze-dried Powder in Improving Gastrointestinal Function
NCT06781814 ·Status: COMPLETED ·Phase: NA
-
Prospective Tolerability Assessment of a Probiotic Dietary Supplement
NCT04044144 ·Status: COMPLETED ·Phase: NA
-
Effect of Probiotics on Regulating Gut Health and Blood Lipid in Adults
NCT06554314 ·Status: RECRUITING ·Phase: NA
-
The Influence of Probiotics on Body Weight and Composition
NCT02465294 ·Status: WITHDRAWN ·Phase: NA
-
The Effect of Probiotics on the Improvement of Digestive Function and Well-being in the Elderly
NCT06648590 ·Status: COMPLETED ·Phase: NA
-
Investigating the Efficacy of Probiotics in Enhancing Gastrointestinal and Immunological Health
NCT06886724 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study to Investigate the Safety and Efficacy of a Probiotic on Gastrointestinal Health in Healthy Adults
NCT04223388 ·Status: UNKNOWN ·Phase: NA
-
Efficacy of Probiotic Against Functional Constipation
NCT06122558 ·Status: RECRUITING ·Phase: PHASE2
-
Exploring the Effects of Probiotics on Workplace Related Stress Symptoms
NCT06381479 ·Status: COMPLETED ·Phase: NA
-
Correlating Probiotic Dietary Supplements During Pregnancy With Maternal Microbiome Profiles
NCT03611647 ·Status: COMPLETED ·Phase: NA
-
Exploring the Effects of Lactobacillus Paracasei PS23 on Workplace-related Stress Symptoms Among Office Workers
NCT05826704 ·Status: TERMINATED ·Phase: NA
-
Preventive Effect of Probiotics in GDM
NCT06938464 ·Status: RECRUITING ·Phase: NA
-
Dose Response Effect of Probiotics for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults
NCT01143623 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
NCT06062472 ·Status: COMPLETED ·Phase: NA
-
Effect of Probiotics on the Digestibility and Immunity in Infants
NCT02317406 ·Status: COMPLETED ·Phase: NA