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Genetic Predictors of Renal Dysfunction Following Heart Transplantation

NCT01686191 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2023-05-10

No results posted yet for this study

Summary

Kidney disease is a common problem after heart transplantation. It may be caused by anti-rejection medications such as cyclosporine or tacrolimus. However, the reason why some people develop kidney problems after a heart transplant, but other people do not, is not fully known. This study plans to learn more about the relationship between a person's genetic make-up (DNA; deoxyribonucleic acid) and the risk of kidney problems after a heart transplant. The long-term goal of this research is to identify genetic variations that may help predict the development of kidney problems after heart transplantation.

Conditions

  • Heart Transplantation
  • Chronic Renal Insufficiency

Sponsors & Collaborators

  • National Jewish Health

    collaborator OTHER

  • University of Colorado, Denver

    lead OTHER

Principal Investigators

  • Christina L Aquilante, Pharm.D. · University of Colorado, Denver

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01686191 on ClinicalTrials.gov