Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.

Summary

Rural communities in the southern U.S. suffer a disproportionate burden of morbidity and mortality from cardiometabolic disease, with traditional risk factors explaining only a modest proportion of the excess burden of disease. There is considerable evidence that multiple dimensions of sleep health, including sleep duration, efficiency, timing, and regularity, as well as the disorders sleep apnea and insomnia, affect cardiometabolic disease risk. However, there is currently a lack of systematically developed sleep data in rural populations. The RURAL Sleep Study is an ancillary study to a recently initiated longitudinal epidemiology study in rural Appalachia and Mississippi Delta (the RURAL Study). The RURAL Sleep Study will add measures of sleep health to the complex individual, social and environmental factors and health outcome measures being evaluated by the RURAL Study, by incorporating minimally burdensome measures of multiple dimensions of sleep health. The results are expected to inform health care providers, public health officials, and the general public of the prevalence, risk factors, and consequences of impaired sleep health in these rural communities, providing a critical basis for prevention, recognition, and management of sleep disorders and improvement of sleep and cardiometabolic health.

Conditions

• Sleep Apnea
• Insomnia
• Sleep Deprivation
• Sleep Disorders, Circadian Rhythm
• Sleepiness, Excessive Daytime
• Fatigue

Sponsors & Collaborators

• University of Alabama at Birmingham

  collaborator OTHER

• Emory University

  collaborator OTHER

• University of Pennsylvania

  collaborator OTHER

• University of Massachusetts, Worcester

  collaborator OTHER

• The University of Texas Health Science Center at San Antonio

  collaborator OTHER

• Beth Israel Deaconess Medical Center

  collaborator OTHER

• National Heart, Lung, and Blood Institute (NHLBI)

  collaborator NIH

• Brigham and Women's Hospital

  lead OTHER

Principal Investigators

• Daniel J Gottlieb, MD, MPH · Brigham and Women's Hospital

• Tené Lewis, PhD · Emory University

• Tianyi Huang, PhD · Harvard Chan School of Public Health

Eligibility

Min Age

25 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-05-08

Primary Completion

2027-01-31

Completion

2027-01-31

Countries

• United States

Study Locations