Exploration of Gait Biomechanics and Pain
NCT06330402 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2025-10-01
Summary
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental knee pain. The main questions it aims to answer are:
* How do gait patterns change during painful walking?
* Can pain sensitivity testing and gait biomechanics predict experimental knee pain intensity?
Participants will receive two knee injections: a) Hypertonic saline (painful condition) and b) Isotonic saline (control condition).
Conditions
- Pain
- Healthy
Interventions
- OTHER
-
Hypertonic saline injection
0.25 mL injection with hypertonic saline (7%) to the infrapatellar fat pad.
- OTHER
-
Isotonic saline injection
Control injection with 0.25 mL isotonic saline (0.9%) to the infrapatellar fat pad.
Sponsors & Collaborators
-
Kristian Kjær Petersen
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-09-26
- Primary Completion
- 2025-02-01
- Completion
- 2025-09-01
Countries
- Denmark
Study Locations
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