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Effect of Knee Pain on Walking Biomechanics

NCT05670236 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2025-10-29

Study results available
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Summary

The goal of this study is to determine if pain in one knee influences loading of the other knee during different types of walking. The main questions it aims to answer are:

* How does unilateral knee pain affect contralateral knee joint loading during different types of walking?
* Does movement and loading change at the hips, knees, and ankles during prolonged walking in persons with painful knee osteoarthritis?

Participants will:

* Fill out questionnaires/surveys
* Complete clinical examinations
* Walking on a treadmill under different types of walking conditions
* Receive two knee injections For comparison purposes, researchers will also enroll healthy participants.

Conditions

  • Osteoarthritis, Knee

Interventions

DRUG

Lidocaine Hydrochloride

10 mL of 1% lidocaine hydrochloride for each intraarticular knee injection

Sponsors & Collaborators

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Patrick Corrigan, DPT, PhD · The Cleveland Clinic

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-25
Primary Completion
2024-07-19
Completion
2024-07-19
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05670236 on ClinicalTrials.gov