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Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients

NCT06286163 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2025-02-07

No results posted yet for this study

Summary

This study is being done in order to understand what causes people to have a chronic cough, which is defined as a cough lasting for more than 8 weeks. The research team wish to find out whether there is any inflammation in the lungs of patients with chronic cough. The research team will also determine whether a suspected chemical produced in the body, called adenosine triphosphate (ATP) can be responsible for causing the chronic cough. In order to be able to find out what is abnormal in those who have a chronic cough, The research team will need to compare their results with those that do not have a chronic cough.

In this study, the research team will examine 10 participants who suffer from chronic cough and 8 individuals who do not have a chronic cough and are healthy.

Conditions

  • Chronic Cough

Sponsors & Collaborators

Principal Investigators

  • Kian Fan Chung, MD · Imperial College London

Eligibility

Min Age
30 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06286163 on ClinicalTrials.gov