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Markers for Chronic Obstructive Pulmonary Disease (COPD)

NCT00180622 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2019-07-05

No results posted yet for this study

Summary

The primary aim of this study is to exploit a difference between COPD patients, chronic smokers without COPD and healthy non-smoking subjects. This will help to assess the utility of inflammatory and oxidative markers in exhaled air and sputum and to compare them with the lung function, clinical parameters and computerised tomography (CT).

Conditions

  • Healthy Non-smokers
  • Current Smokers
  • COPD Patients

Interventions

PROCEDURE

Spirometry

PROCEDURE

Exhaled Nitric Oxide and Carbon Monoxide

PROCEDURE

Exhaled Breath Condensate

PROCEDURE

Induced Sputum

PROCEDURE

CT Scan

PROCEDURE

Blood test

PROCEDURE

St Georges Questionnaire

PROCEDURE

Bodypletysmography

Sponsors & Collaborators

  • AstraZeneca

    collaborator INDUSTRY

  • Imperial College London

    lead OTHER

Principal Investigators

  • Sergei A Kharitonov, MD PhD · Imperial College London

  • Peter J Barnes, MA DM DSc FRCP · Imperial College London

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-07-01
Primary Completion
2002-07-01
Completion
2002-07-01

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00180622 on ClinicalTrials.gov