Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control

Summary

The main objective is to estimate the annual symptomatic incidence of Bordetella pertussis and RSV infections in patients aged 18 years and over with asthma, which will be identified by PCR, for Bordetella pertussis and by PCR for RSV performed at a specific timepoint from onset of symptoms for each symptomatic Acute Respiratory Infection (ARI).

A multicentre prospective cohort study will be undertaken in Spain. Thirty-five centres from different autonomous communities in Spain will participate in the study.

Participants will be asked to report to the investigator if they experience an asthma exacerbation or symptoms of acute respiratory infection with 2 years follow up

Conditions

• Asthma
• Pertussis
• RSV Infection

Interventions

DIAGNOSTIC_TEST

PCR

Depending on the symptoms presented and date of symptom onset, for pertussis, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 3 weeks For RSV, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 72 hours.

Sponsors & Collaborators

• Translational Research In Airway Diseases Group (TRIAD)

  collaborator UNKNOWN

• CIBER of Respiratory Diseases CIBERES

  collaborator UNKNOWN

• Complexo Hospitalario Universitario de A Coruña

  collaborator OTHER

• Hospital de Galdakao

  collaborator OTHER

• Hospital Universitario Doctor Peset

  collaborator OTHER

• Hospital San Pedro de Alcantara

  collaborator OTHER

• Hospital Universitario Marqués de Valdecilla

  collaborator OTHER

• Hospital Universitario Vall d´Hebron

  collaborator UNKNOWN

• Universitat Autonoma de Barcelona

  collaborator OTHER

• Universidade de Santiago de Compostela

  collaborator UNKNOWN

• Consortium for Biomedical Research in Epidemiology and Public Health

  collaborator UNKNOWN

• Hospital Universitario Virgen del Rocio

  collaborator UNKNOWN

• Fundación de Investigación Biomédica - Hospital Universitario de La Princesa

  collaborator OTHER

• University Hospital Virgen de las Nieves

  collaborator OTHER

• Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  collaborator OTHER

• Germans Trias i Pujol Hospital

  collaborator OTHER

• Hospital of Navarra

  collaborator OTHER

• Hospital Universitario de Jerez de la Frontera

  collaborator UNKNOWN

• Hospital El Bierzo

  collaborator OTHER

• Hospital Clinico Universitario San Cecilio

  collaborator OTHER

• Hospital Donostia

  collaborator OTHER

• Hospital Universitario Central de Asturias

  collaborator OTHER

• Hospital Universitario de la Ribera

  collaborator UNKNOWN

• Hospital Costa del Sol

  collaborator OTHER

• Hospital General Universitario Dr. Balmis

  collaborator UNKNOWN

• Hospital de Sagunto

  collaborator OTHER

• Hospital Lluis Alcanyís de Xàtiva

  collaborator UNKNOWN

• Hospital Universitario Lucus Augusti

  collaborator OTHER

• Hospital del Mar

  collaborator OTHER

• Hospital Universitario Virgen de la Arrixaca

  collaborator OTHER

• Hospital Clinic of Barcelona

  collaborator OTHER

• Hospital Clinico Universitario de Santiago

  lead OTHER

Eligibility

Min Age

18 Years

Max Age

99 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-12-21

Primary Completion

2024-07-31

Completion

2026-07-01

Countries

• Spain

Study Locations