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Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study.

NCT04077697 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2019-09-04

No results posted yet for this study

Summary

Invasive tracheobronchial aspergillosis (ITBA) is an uncommon, but severe clinical form of Invasive Pulmonary Aspergillosis (IPA) in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree. In view of the limited data concerning critically ill patients admitted to the intensive care unit (ICU) with severe influenza associated with ITBA, the investigators decided to evaluate the differences between the clinical presentations of two invasive infections: ITBA and IPA without tracheobronchial involvement (No ITBA).

Conditions

  • Invasive Pulmonary Aspergillosis
  • Morality

Interventions

DIAGNOSTIC_TEST

RT-PCR for influenza

influenza real time polymerase chain reaction (RT-PCR) from a nasopharyngeal swab or bronchoalveolar lavage (BAL) fluid.

Sponsors & Collaborators

  • University Hospital, Lille

    collaborator OTHER

  • Centre Hospitalier de Lens

    collaborator OTHER

  • Centre Hospitalier Universitaire, Amiens

    lead OTHER

Principal Investigators

  • Elie Zogheib, MD · CHU Amiens

  • Taieb Chouaki, MD · CHU Amiens

  • Hervé Dupont, Pr · CHU Amiens

  • Julien Maizel, Pr · CHU Amiens

  • Rémy Nyga, MD · CHU Amiens

  • Ivona Milic, MD · CHU Amiens

  • Saad NSEIR, Pr · CHU Lille

  • Boualem SENDID, Pr · CHU Lille

  • Malcom LEMYSE, MD · CHU Lens

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-07-01
Primary Completion
2019-07-16
Completion
2019-07-16

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04077697 on ClinicalTrials.gov