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Association of Dysbiosis and Immune Response in Bronchiolitis in Under 12 Months -Old Infants

NCT06161285 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2025-02-26

No results posted yet for this study

Summary

Acute bronchiolitis is a common disease in children under the age of two, caused mainly by the respiratory syncytial virus (RSV). Furthermore, given the same medical history, it is still very difficult to predict the course and severity of the infection at the onset of symptoms, Some studies have highlighted the importance of the microbiota (intestinal, oral or nasopharyngeal) and of the immune response to RSV in children, We will include 80 children under 2 years old with hospitalized bronchiolitis and non-hospitalized bronchiolitis. Oral, nasal and stool samples will be taken to study the various microbiota in search of dysbiosis. A capillary blood sample will be taken for immune studies.

Conditions

  • Bronchiolitis

Interventions

OTHER

Sampling

Single-time sampling of respiratory virus-infected children

Sponsors & Collaborators

  • Infectious Diseases Models for Innovative Therapies center

    collaborator UNKNOWN

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Etienne BIZOT, Doctor · AP-HP Hôpital Antoine Beclere

Eligibility

Min Age
1 Day
Max Age
12 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-06
Primary Completion
2026-03-31
Completion
2026-04-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06161285 on ClinicalTrials.gov