Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline

NCT06281652 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-03-25

No results posted yet for this study

Summary

The goal of this clinical trial\]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:

* Do Go and Chess improve cognition?
* Is a game better than the other? Is the effect of both games on cognition synergistic?
* Do Go and Chess improve quality of life?
* Do Go and Chess improve mood?
* Do Go and Chess improve lifestyle?

Participants will be randomized to one of four groups:

* Group intervention with Go, once a week, for 12 weeks
* Group intervention with Chess, once a week, for 12 weeks
* Group intervention with Go and Chess, twice a week, for 12 weeks
* Control group

Conditions

Interventions

OTHER

Go classes

Classes of board games (Go), performed in groups of 6-10 subjects, once a week

OTHER

Chess classes

Classes of board games (Chess), performed in groups of 6-10 subjects, once a week

Sponsors & Collaborators

  • University of Milano Bicocca

    lead OTHER

Principal Investigators

  • Lucio Tremolizzo, MD, PhD · Fondazione IRCCS San Gerardo

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-13
Primary Completion
2025-02-13
Completion
2025-02-13

Countries

  • Italy

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06281652 on ClinicalTrials.gov