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Effectiveness of Propolis Mouthwash on Gingivitis

NCT04032548 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2019-07-30

No results posted yet for this study

Summary

Mouthrinses have been in used for centuries as breath fresheners, medicaments, and antiseptics. Recently, propolis has caught the eyes of dentists worldwide and researches are being carried out to infuse the usage of propolis in the dental health care treatments. There is belief that propolis may have a role as a tooth decay prophylaxis and help heal oral ulcers. Propolis is used as mouthwash, toothpaste, oral gel, and throat lozenges because of its proclaimed antibacterial and anti-inflammatory properties. Propolis has shown activity against common periodontal microorganisms, such as Candida species and the Streptococci mutans in vitro studies. Till date, no study has evaluated the clinical and microbiological effects of Malaysian Propolis as a mouthwash. Thus, the present study is designed to evaluate the effectiveness of Propolis as a mouthwash in the reduction of Plaque and gingivitis.The aim of the study is to assess and compare the effectiveness of Propolis mouthrinse with Chlorhexidine mouthrinse.

Conditions

  • Gingivitis

Interventions

DRUG

Placebo mouthwash

After using mouthwash for 21 days, they are instructed to refrain from mouthwash for 14 days (wash out period).

DRUG

Propolis mouthwash

After using mouthwash for 21 days, they are instructed to refrain from mouthwash for 14 days (wash out period).

DRUG

Chlorhexidine mouthwash

After using mouthwash for 21 days, they are instructed to refrain from mouthwash for 14 days (wash out period).

Sponsors & Collaborators

  • Mahsa University

    lead OTHER

Principal Investigators

  • Shilpa Gunjal, Ph.D · Mahsa University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-18
Primary Completion
2019-03-11
Completion
2019-06-05

Countries

  • Malaysia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04032548 on ClinicalTrials.gov