MedTrace Logo

The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

NCT06207253 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2025-05-30

No results posted yet for this study

Summary

The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis.

The main question\[s\] it aims to answer are:

• Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.

Conditions

  • Endodontic Disease
  • Pulp Disease, Dental
  • Intracanal Medication

Interventions

DRUG

Diclofenac Sodium

placement of intracanal medication for the three groups will be done after cleaning and shaping of the root canals and it will be left for one week.

DRUG

Calcium hydroxide

placement of intracanal medication for the three groups will be done after cleaning and shaping of the root canals and it will be left for one week.

Sponsors & Collaborators

  • British University In Egypt

    lead OTHER

Principal Investigators

  • Shehab Eldin M Saber, doctoral · british university in Egypt- dentistry collage

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-11-30
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06207253 on ClinicalTrials.gov