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Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain

NCT06090500 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2024-02-08

No results posted yet for this study

Summary

The goal of this clinical trial is to compare submucosal Cryotherapy with different anti-inflammatory drugs in the reduction of post-endodontic pain in upper premolars with symptomatic irreversible pulpitis.

The main question it aims to answer is:

Is there is a difference in post-endodontic pain intensity following submucosal cryotherapy or anti-inflammatory drugs injection in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment preceded by preoperative injection of cold saline (cryotherapy) or preoperative injection of anti-inflammatory drugs Researchers will compare \[Cryotherapy, Non steroidal anti-inflammatory drugs, steroids and no intervention\] to see the intensity of post-endodontic pain.

Conditions

  • Post-endodontic Pain

Interventions

PROCEDURE

Cryotherapy

preoperative submucosal infiltration injection of cold saline solution (2-5 degrees Celsius)

PROCEDURE

Diclofenac sodium

preoperative submucosal infiltration injection of Diclofenac sodium (25mg/ml)

PROCEDURE

Dexamethasone sodium phosphate

preoperative submucosal infiltration injection of dexamethasone sodium phosphate (4mg/ml)

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-20
Primary Completion
2024-01-05
Completion
2024-01-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06090500 on ClinicalTrials.gov