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MicroRNAs as Biomarkers for Obstructive Sleep Apnea

NCT06189755 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2025-07-18

No results posted yet for this study

Summary

Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop and validate blood biomarkers that are specific to OSA, useful for identification of cases with OSA, reflective of efficacy of therapy, and able to predict blood pressure response to treatment of OSA.

Conditions

Interventions

DEVICE

Positive Airway Pressure

Case participants will use Positive Airway Pressure (PAP) treatment as part of routine clinical care.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • University of Pennsylvania

    lead OTHER

Principal Investigators

  • Allan I Pack, MBChB, PhD · University of Pennsylvania

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-01
Primary Completion
2027-11-01
Completion
2028-04-30

Countries

  • United States
  • Iceland

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06189755 on ClinicalTrials.gov