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Identification of Biomarkers for Obstructive Sleep Apnoea Syndrome

NCT02043483 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2015-02-18

No results posted yet for this study

Summary

Untreated Obstructive Sleep Apnea Syndrome (OSAS) has long-term complications, namely metabolic imbalances (obesity, dislipidemia, type 2 diabetes mellitus). Until now, no molecular markers for this physiopathological connection have been identified.

This project aims to determine non-invasive biomarkers that may allow better comprehension of the metabolic consequences of OSAS, as well as assess the effect of Continuous positive airway pressure (CPAP) on these metabolic parameters.

This project will integrate the clinical, metabolic, genetic/proteomic and biologic systems to further explore the mechanisms behind OSAS, as well as the effect of the treatment with CPAP.

Conditions

  • Obstructive Sleep Apnoea Syndrome

Sponsors & Collaborators

  • Centro de Estudos de Doenças Crónicas

    collaborator OTHER

  • NOVA Medical School

    collaborator OTHER

  • Centro Hospitalar Lisboa Norte

    collaborator OTHER

  • Instituto Nacional de Saúde Dr. Ricardo Jorge

    collaborator UNKNOWN

  • Biotempo

    collaborator UNKNOWN

  • Fundação para a Ciência e a Tecnologia

    collaborator OTHER

  • Universidade Nova de Lisboa

    lead OTHER

Principal Investigators

  • Amélia Feliciano, MD · Centro Hospitalar Lisboa Norte

Eligibility

Min Age
25 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02043483 on ClinicalTrials.gov